PDE inhibitors for the treatment of erectile dysfunction. WHY?? [p___eAjMOpe]

In this video, the discussion on why PDE (phosphodiesterase) inhibitors are used in erectile dysfunction. For penile erection, there is a release of NO (nitric oxide) which is a vasodilator. NO activates guanylyl cyclase to increase cGMP which gets degraded by PDE-5. PDE-5 inhibitor preserves cGMP. Drugs like sildenafil (viagra) and tadalafil act via this mechanism. Channel details: Welcome to my physiology learning channel. I am Dr. Ramkumar S MBBS, MD, DNB physiology. Explain why series will help you to understand concepts in physiology, solve MCQs, answer in Viva, and theory exams. Happy Learning. #physiology #explainwhyseries #PDEinhibitor #erectiledysfunction #sildenafil Suggested book links For MBBS students Ganong’s Review of Medical Physiology - Guyton and Hall Textbook of Medical Physiology - For Postgraduates in Physiology Berne and Levy Physiology - Boron Physiology - Gadgets to make video Iphone - Screen recording - Writing - Lighting - Softbox - Mic - Tripod - Mobile holder - #male enhancement african herbs #organic penis enlargement #extenze male enhancement gnc